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Haşimato hastalığı nasıl tedavi edilir-Haşimato hastalığının tedavisiyorum yapılmamış

Haşimato hastalığı nasıl tedavi edilir-Haşimato hastalığının tedavisi

Haşimato hastalığı nasıl tedavi edilir-Haşimato hastalığının tedavisiTiroid hücrelerine karşı vücudumuzun ürettiği antikorlar sonucu oluşan tiroid iltihabına haşimato hastalığı denir.
Tiroid antikoru nedir: Vücudumuzu mikroplara bakteri, virüs karşı koruyan bir sistem vardır. Buna bağışıklık sistemi immün sistem denir. Bu sistem, aynı sinir sistemi veya sindirim sistemi gibi bir sistemdir. Bağışıklık sistemi akciğer, kemik iliği, dalak ve karaciğerde yerleşmiş bir grup hücreden oluşur. Bu hücrelerin ana görevlerinden biri de mikroplarla savaşmak için antikor dediğimiz molekülleri üretip kana vermektir. Üretilen bu antikorlar çok yararlıdır.

Ancak, bağışıklık sisteminin yanlışlıkla veya şaşırarak ürettiği bazı antikorlar oto-antikorlar tiroid hücrelerinde bulunan peroksidaz enzimi ile tiroglobulin isimli moleküle karşı etkili olurlar. Bunlara oto-antikor denilir. Bu antikorlar çok zaralıdır, çünkü tiroid hücrelerine gidip yapışır ve onları aynı bir mikropmuş gibi tahrip eder. Tiroide bir iltihabi durum (“tiroidit”) ortaya çıkar. Bu iltihap ve harabiyet sonucunda hormon üreten tiroid hücreleri çalışamaz hale gelir, kandaki tiroid hormon (tiroksin) düzeyi düşer, TSH düzeyi artar.

Bu antikorların teşhiste en yaygın olarak kullanılanları anti-TPO (anti-tiroid peroksidaz) ve anti-TG (anti-tiroglobulin) antikorları olarak isimlendirilir. Bu antikorların ölçümü tiroid hastalığının türünün anlaşılmasında ve “tiroidit” hastalığının (tiroid’in iltihabı) tanısında çok önemli olabildiği gibi bu hastalığın daha sonraki takibinde de kullanılmaktadır.

Oto-antikorlar neden yükselir? Tam olarak bilinmiyor ancak tetikleyen faktörler sayılabilir. Üst solunum yolu enfeksiyonu, ani yoğun üzüntü, gerekmediği halde sürekli iyotlu tuz kullanımı suçlanan faktörler arasındadır. Antikor yüksekliği, ailsel geçiş (genetik) göstermektedir.

Oto-antikorlar ne yapar? Bu antikorlar yükselince, ya hastada hipotiroidizm (tiroid hormon yetmezliği: örneğin Haşimato hastalığı) veya daha seyrek olarak hipertiroidizm (zehirli guatr: örneğin Basedow Graves hastalığı) oluşabilir. Oto-antikorları yüksek olanlarda tiroid’in papiller kanseri daha sık görülmektedir.

Nasıl tedavi edilir? Sadece tiroid hormonu vermekle tedavi tamamlanmaz, bir yandan da antikorları düşürecek tedavi de uygulanmalıdır.

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